Complete remission of acute leukemia for more than seven years. A report on 100 children
Schaison, G.; Jacquillat, C.; Lemercier, N.; Alby, N.; Weil, M.; Auclerc, M.F.; Boiron, M.; Bernard, J.
Annales de Medecine Interne 131(2): 84-86
1980
ISSN/ISBN: 0003-410X PMID: 7396325 Document Number: 164656
A total of 1200 children were treated for leukemia between 1958 and 1971, and 100 of these cases have had an uninterrupted remission for more than seven years: 10 children who relapsed at an early stage have had no further relapses; 93 are alive and in remission after discontinuation of treatment for between 1 and 12 years. Five of the children relapsed and four of these are in remission again. Two children died, one from a hepatocarcinoma and the other after cardiac failure of late onset. A study of these children showed that: 1 - growth rate was normal, 2 - puberty occurred at a normal age, and procreation was possible as 10 children were born from parents who had recovered after having leukemia, 3 - school-work and subsequent social and occupational behaviour were satisfactory, 4 - late psychological repercussions were absent or mild. Long-term prognosis appears to be good, and no other blood disorder has been reported in those cases that have recovered from the leukemia.