Beta-chain contact sites in the haemoglobin S polymer
Nagel, R.L.; Johnson, J.; Bookchin, R.M.; Garel, M.C.; Rosa, J.; Schiliro, G.; Wajcman, H.; Labie, D.; Moo-Penn, W.; Castro, O.
Nature 283(5750): 832-834
1980
ISSN/ISBN: 0028-0836 PMID: 7360228 Document Number: 164064
The amino acid residues involved in the areas of contact that stabilise the haemoglobin S polymer fibre seem to be the same ones that stabilise the basic unit of the deoxyhaemoglobin S crystal: the Wishner-Love double strand. The haemoglobin S fibre is probably formed by a unique packing of these double strands.
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