Comparison between anatomical subsegmentectomy and nonanatomical partial resection for hepatocellular carcinoma located within a single subsegment: a single-center retrospective analysis

Yamamoto, T.; Yagi, S.; Kita, R.; Masui, H.; Kinoshita, H.; Sakamoto, Y.; Okada, K.; Miki, A.; Kondo, M.; Hashida, H.; Kobayashi, H.; Uryuhara, K.; Kaihara, S.; Hosotani, R.

Hepato-Gastroenterology 62(138): 363-367

2015


ISSN/ISBN: 0172-6390
PMID: 25916064
Document Number: 16337
For hepatocellular carcinoma (HCC) within a single subsegment, the superiority of anatomical subsegmentectomy over non-anatomical partial resection is still controversial. In this study, we assessed the potential benefit of subsegmentectomy. We selected 44 patients with a single HCC lesion within one subsegment who had undergone anatomical subsegmentectomy or non-anatomical partial resection from among 173 patients who underwent hepatectomy in our hospital from August 2003 to May 2013. We compared the results following anatomical subsegmentectomy (Group A; n = 16) and non-anatomical partial resection (Group N; n = 28). One- and two-year survival rates were 92.5% and 89.3%, respectively; 1- and 2-year recurrence-free survival (RFS) rates were 88.9% and 69.1%, respectively. There was no significant difference in overall survival or RFS between the groups. However, among HBV-positive patients, RFS was significantly better for Group A than Group N (p = 0.008). For HBV-positive HCC within a single subsegment, we recommend subsegmentectomy.

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Comparison between anatomical subsegmentectomy and nonanatomical partial resection for hepatocellular carcinoma located within a single subsegment: a single-center retrospective analysis