Keratoacanthoma with Osteolysls
Mehta, V.R.
Indian Journal of Dermatology Venereology and Leprology 46(6): 360-363
1980
ISSN/ISBN: 0378-6323 PMID: 28218126 Document Number: 161963
Subungual keratoacanthoma with osteolysis of the terminal phalanx was first described by Fisher as part of a multiple keratoacanthoma syndrome. An isolated interdigital lesion is described. Following a thorn prick a keratotic lesion evolved between the right 3rd and 4th toes of a 50-yr-old male. Osteolysis of the proximal and middle phalanges of the 3rd toe was demonstrated radiologically. A cup shaped lesion with buttress formation and proliferative epidermal changes in its base with dyskeratosis, para- and orthohyperkeratosis and exocytosis constituted the dominant histologic findings. Partial spontaneous resolution was observed.