Metabolic shifts during the repeated administration of analeptics in alcoholic intoxication
Bender, K.I.; Bobrova, L.A.; Kupchikov, V.V.
Farmakologiia i Toksikologiia 43(2): 202-205
1980
ISSN/ISBN: 0014-8318 PMID: 6108235 Document Number: 161690
It was shown in experiments on rabbits that under acute alcohol poisoning of medium degree, repeated administration of caffeine (10 mg/kg) and bemegrid in particular (5 mg/kg) promotes aerobization of the oxidative processes and mobilizes the respiratory mechanism of metabolic acidosis compensation. Under these conditions, ethimizol (10 mg/kg) stimulates the respiratory center and promotes (to a less measure) aerobization of the metabolic processes in tissues and ethanol elimination.