Effect of circulating insulin on liver damage by CCl4 in the rat. II. Histological aspects
Torella, R.; Improta, L.; Scognamiglio, G.; Siniscalchi, N.; Jori, G.P.
Bollettino della Societa Italiana di Biologia Sperimentale 56(9): 874-878
1980
ISSN/ISBN: 0037-8771 PMID: 7448086 Document Number: 161498
The authors have studied the damaging effects of CCl4 (0.05ml/Kg) in healthy rats, in alloxan diabetic rats and in rats treated with tolbutamide per os (100mg/Kg) for twenty days. Histological studies in these animals demonstrated that actually hyperinsulinemia has a slight protective action on damage produced by CCl4 on rat liver.
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