Comparative studies on Corynebacterium pyogenes toxin formation in monocultures and mixed cultures. the demonstration of a stimulating effect of Peptococcus indolicus and Stuart-Schwan cocci
Sørensen, G.H.
Acta Veterinaria Scandinavica 21(3): 438-447
1980
ISSN/ISBN: 0044-605X PMID: 7004149 Document Number: 160946
The growth and the toxin (i.e., hemolysin) producing capacity of C. pyogenes were studied in monocultures and in cocultures with 1 or more of the organisms frequently accompanying it in summer mastitis in cattle (P. indolicus, Stuart-Schwan cocci, Bacteroides melaninogenicus ssp. levii, Fusobacterium necrophorum and Streptococcus dysgalactiae) or with organisms seldom associated with summer mastitis (Streptococcus uberis, Streptococcus agalactiae, non-toxic staphylococci and Escherichia coli). P. indolicus and Stuart-Schwan cocci to some extent stimulated the growth and hemolysin producing capacity of C. pyogenes, while S. dysgalactiae, S. uberis, S. agalactiae, E. coli and the majority of the staphylococci reduced these activities. Most F. necrophorum strains stimulated growth but not hemolytic activity. With B. melaninogenicus the results were inconclusive. The effect of P. indolicus appeared to be associated with the production of a filterable factor. Mouse toxicity and hemolytic activity of culture filtrates were closely correlated.