In vitro effect of 5 alpha-androstane-3 beta, 17 beta diol on the liberation of follicle stimulating hormone (FSH) induced by LH-RH
Girre, A.; Gaubicher, J.; Rault, B.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 174(6): 948-956
1980
ISSN/ISBN: 0037-9026 PMID: 6451270 Document Number: 160339
A continuous flow incubation (perifusion) was used to examine the effect of 5 alpha-androstane-3 beta, 17 beta diol 3 beta diol) on the release of FSH induced by LH-RH. Over a 3 h-period the 3 beta diol exerts inhibitory effects on male and female pituitaries at high dose (1 microgram/ml) and only on male pituitaries at low dose (100 ng/ml).
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