In vitro secretion of follicle-stimulating hormone by pituitary chromophobe adenomas
Takeuchi, J.; Handa, H.; Suda, K.; Aso, T.
Surgical Neurology 14(4): 303-309
1980
ISSN/ISBN: 0090-3019 PMID: 6776644 Document Number: 158341
Of 20 female and 14 male patients with chromophobe adenomas, 4 male patients, aged 38 to 47 years, and one female patient, aged 54, showed above normal basal plasma levels of follicle-stimulating hormone (FSH). An in vitro tissue culture study that was performed using chromophobe cells obtained from 3 of the 4 male patients and the 1 female patient showed moderate FSH secretion into the culture media. The secretion of FSH by pituitary chromophobe adenomas might be more frequent than hitherto suspected.
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