A case of follicle-stimulating hormone-secreting pituitary tumor with postoperative elevation of sperm count
Kazama, T.; Oota, S.; Iwaski, M.; Junichou, A.; Sakamoto, M.; Fuse, H.; Katayama, T.; Endo, T.
Japanese Journal of Fertility and Sterility 38(4): 734-738
1993
Document Number: 435385
A follicle-stimulating hormone-secreting pituitary tumor was demonstrated in a 32 year-old man who presented with bilateral hemianopsia. He had no endocrine symptoms. Plasma level of FSH was elevated, and concentrations of other pituitary hormones were all normal. Semen analysis revealed mild oligozoospermia (12-20 times 10-6/ml). Transsphenoidal tumor resection was performed. The tumor was a chromophobe adenoma, and immunohistochemical examination showed that the tumor was FSH-secreting. Postoperative semen analysis showed marked improvement of sperm concentration with reduction in serum FSH levels.