Ultrastructure of the adrenal cortex in burn disease
Smorshok, S.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 89(1): 63-66
1980
ISSN/ISBN: 0365-9615 PMID: 7378572 Document Number: 160020
Submicroscopic changes in adrenocorticocytes and sinusoid capillaries on days, 1, 2, 7, 14, 21 and 28 of burn disease were studied in experiments on pubertal male guinea pigs. During the first week the hormogenic gland cells showed predominant hyperplastic processes which proceeded in the presence of functionally excited sinusoids. On the 14th day the destruction of organella significantly increased along with hyperplasia and hypertrophy in parenchymatous and endothelial cells. Increased disorganization and destruction of the cell membrane components led to dramatic abnormalities in vascular-parenchymatous correlations and to the development of deep dystrophic processes and necrobiotic injuries to the adrenal cortex in later periods of the disease.