Increased immunologic reactivity against hepatoma 22A cells in MTV-infected C3H mice in comparison to MTV-free mice

Lavrovskiĭ, V.A.; Viksler, V.K.

Biulleten' Eksperimental'noi Biologii i Meditsiny 90(10): 467-469

1980


ISSN/ISBN: 0365-9615
PMID: 6252986
Document Number: 158870
Some tumors of no mammary tissue origin (sarcoma, hepatoma) grew more effectively in MTV-free mice (C3Hf) as compared with MTV-infected mice (C3H/He), whereas the tumors of mammary gland origin grew more rapidly in the latter ones. It has been shown that C3H/He mice develop a stronger specific immune reaction against hepatoma 22a cells than do C3H/f mice and that the animals of MTV-bearing subline exhibit a higher natural killer activity against these cells.

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