The effect of anti-T sera on the natural killer activity of the splenocytes in C3HA mice at different times after the transplantation of hepatoma 22a cells
Filatova, N.A.; Malygin, A.M.; Goriunova, L.B.; Fel', V.I.
Tsitologiia 31(10): 1221-1225
1989
ISSN/ISBN: 0041-3771 PMID: 2533419 Document Number: 328542
Suspension of splenocytes of control C3HA mice and mice examined early after transplantation of mouse hepatoma 22a cells were fractionated by treatment with anti-T-sera (anti-thymocytes, antibrain and anti-suppressor-T-cells). This treatment leads to various changes in NK-activity due to elimination of different subpopulations of T-lymphocytes. This variability may be associated with the presence of two or more types of suppressor cells able to influence the NK-cells directly or by means of other immunocompetent cells.