Evaluation of T-lymphocytic activity tested by e rosettes test for rheumatoid arthritis
Scarpa, R.; Postiglione, L.; Riccio, A.; Cutolo, M.; Oriente, P.
Quaderni Sclavo di Diagnostica Clinica e di Laboratorio 16(1): 1-6
1980
ISSN/ISBN: 0033-4979 PMID: 6972543 Document Number: 158064
In a group of 25 patients with rheumatoid arthritis, the percent of erythrocyte rosettes forming cells (ERFC) was found significantly decreased in patients with rheumatoid factor positive (RF+), whereas ERFC were normal in the RF negative patients (RF--). Likely, T-lymphocytic depression in the RF+ patients could be related to a T-suppressor lymphocytes deficit and therefore, B-lymphocytes would be abnormally stimulated. Moreover, in the RF-- patients, B-lymphocytes would not be enhanced for the normal T-suppressor lymphocytes activity.
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