Antibody fixation on cell nucleus in culture

Fizet, D.; Guillet, G.; Thivolet, J.

Pathologie-Biologie 28(9): 581-583

1980


ISSN/ISBN: 0369-8114
PMID: 7003505
Document Number: 157384
Anti-nuclear antibodies which have a speckled nuclear fluorescent pattern (anti-RNP) have been incubated with various cell-cultures: epidermis, placentas, Hela cells, lymphoblasts. These antibodies are fixed in nuclei in vitro but do not affect every nuclear cell. Regulatory factors as mitosis seem to interfere.

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