Chronic infantile lactate acidosis
Papanastasiou, D.; Lehnert, W.; Schuchmann, L.; Hommes, F.A.
Helvetica Paediatrica Acta 35(3): 253-260
1980
ISSN/ISBN: 0018-022X PMID: 7410111 Document Number: 154350
A baby with congenital lactic acidosis is described. The blood levels of lactic acid and alanine as well as the excretion of these compounds in the urine were largely elevated. Clinically the illness presented with vomiting, poor feeding, areflexia, muscular hypotonia and hepatomegaly. The baby died at the age of three months. The pyruvate dehydrogenase complex in cultured fibroblasts showed an activity of 14% of normal values.