Effect of hypervitaminosis a on tongue muscles of the rat. a morphometric study
Lopes, R.A.; Piccolo, A.M.; Petenusci, S.O.; da Costa, J.R.; Campos, G.M.
International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 49(3): 235-239
1979
ISSN/ISBN: 0300-9831 PMID: 528151 Document Number: 153438
Daily administration of 200 I.U. vitamin A/gram body weight to rats, for a period of 10 days, causes generalized hypertrophy of the tongue muscles. The data were confirmed with morphometric techniques, consisting of increased cytoplasm and decreased nuclei and empty spaces, obtained by the Chalkley technique, nuclei of similar volume, obtained with the use of karyometry, and larger areas of cross-sections of muscle fibers.