The basic science of dermal fillers: past and present Part I: background and mechanisms of action
Gilbert, E.; Hui, A.; Waldorf, H.A.
Journal of Drugs in Dermatology Jdd 11(9): 1059-1068
2012
ISSN/ISBN: 1545-9616 PMID: 23135648 Document Number: 15256
Dermal fillers have provided a safe and effective means for aesthetic soft tissue augmentation, and have experienced a dramatic increase in popularity during the past 10 years. Much focus has been placed upon filler technique and patient outcomes. However, there is a relative lack of literature reviewing the basic science of dermal fillers, which is vital to a physician's understanding of how each product behaves in vivo. Part I of this article reviews the basic science and evolution of both historical and contemporary dermal fillers; Part II examines their adverse effects. We endeavor to provide the physician with a practical approach to choosing products that maximize both aesthetic outcome and safety.
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