Serotonin and ATP metabolism in the thrombocytes of patients with different stages of cerebrovascular disorders of the ischemic type
Korovin, A.M.; Rudenko, I.I.; Bogoiavlenskaia, N.M.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 79(1): 32-35
1979
ISSN/ISBN: 0044-4588 PMID: 760342 Document Number: 152285
The patients with ischemic lesions of brain circulation showed marked biochemic changes of blood platelets. Obviously it plays an important role in the development of the given pathology. In the acute stage of the stroke there was a decrease of serotonin and ATP content in platelet which gradually increased along with the development of the disease. In the period of the residual phenomena the level of the studied indices appeared significantly increased in comparison with the normal one. In the patients with transferred lesions of the brain circulation at the acute stage serotonin and ATP content was not below the normal level. Later on the increase of these parameters took place and in the period of the residual phenomena theirlevel in platelet did not differ from serotonin and ATP content in blood platelets of the patients with the ischemic stroke.