Synthesis of spontaneous interferon by mouse peritoneal cells in vitro. II. Characteristics of the process of spontaneous interferon synthesis
Cembrzyńska-Nowak, M.; Blach-Olszewska, Z.
Acta Biologica et Medica Germanica 38(5-6): 775-779
1979
ISSN/ISBN: 0001-5318 PMID: 525152 Document Number: 152129
As it was shown previously that the peritoneal cells of mice were capable of producing interferon spontaneously. Spontaneous interferon appeared after 5 to 6 h of incubation of peritoneal cells at 26 degrees C and its highest level has been found after 12 h. The production of spontaneous interferon was inhibited by 4 h incubation of peritoneal cells at a temperature of 37 degrees C as well as by actinomycin D added at 0 to 4 h.