Effect of ethanol and acetaldehyde on the positive reinforcement structures in rats
Burov, I.V.; Borisenko, S.A.
Farmakologiia i Toksikologiia 42(3): 291-293
1979
ISSN/ISBN: 0014-8318 PMID: 446715 Document Number: 151932
An activating action of low doses of ethanol and depressant action of acetaldehyde on the hypothalamic and septal structures of positive reinforcement was established in rat experiments using the method of self-stimulation. The relationship between ethanol activating action on these structures and its increased consumption in the conditions of free choice between ethanol and water was demonstrated.
Document emailed within 1 workday
Related Documents
Nuzhnyĭ, V.P.; Zabirova, I.G.; Abdrashitov, A.K. 1988: Effect of acetaldehyde, sodium acetate, ethanol and the combination of ethanol with pyrazole on the manifestation of the cardionecrotic action of adrenaline in rats Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 5: 18-20Bardina, L.R.; Satanovskaia, V.I.; Pron'ko, P.S.; Kuz'mich, A.B. 1997: Activity of the enzymes of ethanol and acetaldehyde metabolism in rats with varying initial sensitivity to alcohol Ukrainskii Biokhimicheskii Zhurnal 69(1): 94-99
Vikhliaev, I.I.; Artemenko, G.N.; Voronina, T.A.; Ul'ianova, O.V.; Nerobkova, L.N. 1979: Effect of piracetam on some manifestations of the effects of ethanol and acetaldehyde Farmakologiia i Toksikologiia 42(1): 76-81
Lin, D.C. 1975: Brain and blood levels of ethanol and acetaldehyde in strains of mice with different preferences for ethanol Research Communications in Chemical Pathology and Pharmacology 11(3): 365-371
Morozov, I.E.; Salomatin, E.M.; Okhotin, V.E. 2002: Brain acetaldehyde and ethanol: method of determination and diagnostic significance in ethanol poisoning Sudebno-Meditsinskaia Ekspertiza 45(2): 35-40
Jauhonen, P.; Baraona, E.; Miyakawa, H.; Lieber, C.S. 1982: Origin of breath acetaldehyde during ethanol oxidation. Effect of long-term cigarette smoking Journal of Laboratory and Clinical Medicine 100(6): 908-916
Altomare, E.; Grattagliano, I.; Didonna, D.; Gentile, A.; Vendemiale, G. 1998: Gastric and intestinal ethanol toxicity in the rat. Effect on glutathione level and role of alcohol and acetaldehyde metabolisms Italian Journal of Gastroenterology and Hepatology 30(1): 82-90
Riveros-Rosas, H.; Julian-Sanchez, A.; Pinã, E. 1997: Enzymology of ethanol and acetaldehyde metabolism in mammals Archives of Medical Research 28(4): 453-471
Belykh, A.G.; Strelkov, R.B. 1987: Influence of hypoxia on the effects of ethanol and acetaldehyde Farmakologiia i Toksikologiia 50(6): 89-91
Ovcharov, R.G.; Bantutova, I.I.; Iosifov, T.I. 1983: Effect of GABA-ergic substances on the elaboration of conditioned reflexes in rats under negative reinforcement Farmakologiia i Toksikologiia 46(6): 17-20
Lamboeuf, Y.; Latge, C.; Roumec, C.; de Saint Blanquat, G. 1987: Ethanol tolerance in the rat after inhalation of acetaldehyde for a period of 21 days Alcohol and Alcoholism . Suppl 1: 441-447
Fukunaga, T.; Yamamoto, K.; Adachi, J.; Ueno, Y.; Mizoi, Y. 1989: Partition ratio of acetaldehyde between blood and breath after ethanol consumption Arukoru Kenkyu to Yakubutsu Izon 24(5): 405-416
Błasiak, J. 2001: Ethanol and acetaldehyde impair the repair of bleomycin-damaged DNA in human lymphocytes Cytobios 106(Suppl 2): 141-149
Altura, B.M.; Altura, B.T. 1982: Microvascular and vascular smooth muscle actions of ethanol, acetaldehyde, and acetate Federation Proceedings 41(8): 2447-2451
Solomon, L.R.; Crouch, J.Y. 1990: Delta-Aminolevulinic acid dehydratase in rat liver: studies on the effects of ethanol, acetaldehyde, and B6 vitamers Journal of Laboratory and Clinical Medicine 116(2): 228-236
Jones, A.W.; Neiman, J.; Hillbom, M. 1987: Elimination kinetics of ethanol and acetaldehyde in healthy men during the calcium carbimide-alcohol flush reaction Alcohol and Alcoholism . Suppl 1: 213-217
Spivak, K.J.; Amit, Z. 1987: The role of acetaldehyde-metabolizing enzymes in the mediation of ethanol consumption: an investigation using a simulated drinking bout Alcohol and Alcoholism . Suppl 1: 361-365
Shiraishi, K.; Tsuruya, K.; Anzai, K.; Arase, Y.; Hirose, S.; Kagawa, T.; Mine, T.; Matsuzaki, S. 2015: Effects of ethanol and acetaldehyde load on erythrocyte deformability in healthy subjects and patients with liver cirrhosis Nihon Arukoru Yakubutsu Igakkai Zasshi 50(1): 13-18
Tobon, F.; Mezey, E. 1971: Effect of ethanol administration on hepatic ethanol and drug-metabolizing enzymes and on rates of ethanol degradation Journal of Laboratory and Clinical Medicine 77(1): 110-121
Matsuzaki, S.; Gordon, E.; Lieber, C.S. 1981: Increased alcohol dehydrogenase independent ethanol oxidation at high ethanol concentrations in isolated rat hepatocytes: the effect of chronic ethanol feeding Journal of Pharmacology and Experimental Therapeutics 217(1): 133-137