Nucleolar DNA organization in the interphase nuclei of mouse fibroblasts
Pouchelet, M.; Anteunis, A.; Gansmüller, A.; Robineaux, R.E.
European Journal of Cell Biology 20(1): 107-112
1979
ISSN/ISBN: 0171-9335 PMID: 391569 Document Number: 150117
The organization of nucleolar DNA in interphase nuclei of somatic cells was studied at the ultrastructural level using oxidized DAB as a nucleic acid stain. Some finely filamentous networks of DNA-containing structures were observed within the nucleolar fibrillar component. They originated from the perinucleolar shell of condensed chromatin and from a chromatinic area with a honeycomb-like structure. The latter was significantly associated with nucleoli and is believed to be a part of the nucleolar organizer region.