Parvoviral enteritis and panleukopenia in dogs
Black, J.W.; Holscher, M.A.; Powell, H.S.; Byerly, C.S.
Veterinary Medicine-Small Animal Clinician 74(1): 47-50
1979
ISSN/ISBN: 0042-4889 PMID: 256349 Document Number: 149367
Among dogs aged between two weeks and one year there was high morbidity and 50% mortality, with a higher prevalence in kennels. Affected animals stopped eating, sometimes vomitted and became depressed. Panleukopenia (500/mm3) was also a feature. Severe haemorrhagic enteritis involving most of the small intestine and, in some cases, the colon was found PM. Denuding of the surface epithelium was common with villi being very short or absent. Antibody to strain TN-233 of canine parvovirus was detected in convalescent dogs. Large numbers of 22 nM spherical particles were found in faeces from infected dogs. These were virions of identical structure to TN-233 isolated from culture and were compatible with those of the parvovirus group. The virus shares neutralizing antibody with feline panleukopenia virus.