Morphological characterisitcs of the pathological process in the central nervous system of monkeys infected with variants of measles virus strain L-16

Sharova, O.K.; Rozina, E.E.; Shteinberg, L.S.; Gordienko, N.M.; Kolyanova, I.S.

Acta Virologica 23(5): 393-397

1979


ISSN/ISBN: 0001-723X
PMID: 42298
Document Number: 149202
The neurovirulence of L-16 vaccine measles virus strains and its 9 clonal variants was investigated in intracerebrally infected Macaca mulatta monkeys. Two groups of clones were distinguished: one comprised variants that caused destructive changes of neurons in the brain and diffuse proliferative gliosis, and the second variants that caused changes of a transitory character, connected with the traumatic exposure.

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