Comparative characteristics of the effect of noninhalational narcotics on the reflex mechanisms of blood circulation regulation
Martiuk, S.A.; Makatun, V.N.; Tsyrlin, V.A.
Farmakologiia i Toksikologiia 42(4): 365-368
1979
ISSN/ISBN: 0014-8318 PMID: 38996 Document Number: 148366
It has been shown in experiments on cats with intact brain, as well as on decerebrated and spinal animals that chloralose, sombrevine and viadril exert no pronounced effect on initial electric activity in the renal nerve or baroreceptor inhibition of the neurogenous vascular tone, but inhibit vasomotor responses at stimulation of highly liminal afferent fibers of the cerebrospinal nerves. In animals with intact brain, sodium hydroxybutyrate inhibiting baroreceptor reflexes enhanced vasomotor reactions caused by activation of cutaneous and visceral nerves.