Duck virus hepatitis: serial passage of attenuated virus in ducklings

Woolcock, P.R.; Crighton, G.W.

Veterinary Record 105(2): 30-32

1979


ISSN/ISBN: 0042-4900
PMID: 233456
Document Number: 145878
The safety of three attenuated virus vaccines of proven efficacy against duck virus hepatitis was assessed by controlled laboratory studies which involved the serial transmission of the virus through groups of 2-day-old ducklings known to be susceptible to the disease. Each vaccine was initially derived from a different source. Enhancement of virulence which resulted in deaths from the disease in test groups of ducklings occurred in each instance.

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