Synthesis and properties of nucleotide derivatives of poly (oligo) -L-lysine

Veĭko, N.N.; Gromova, E.S.; Shabarova, Z.A.

Molekuliarnaia Biologiia 13(3): 595-600

1979


ISSN/ISBN: 0026-8984
PMID: 460205
Document Number: 143605
Nucleotide derivatives (epsilon-amino groups of lysine residues) of lysine residues) of poly(oligo)-L-lysine were synthesized. The structure of the resulting compounds in solution were studied by circular dichroism techniques. Week stacking interactions of the nucleotide bases on the polypeptide template were found to be characteristic of these compounds. It has been shown that the nucleotide derivatives of poly(oligo)-L-lysine are not involved in complementary interactions with the polynucleotides.

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