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Affinity for measles virus anti-haemolysin of a residual immunoglobulin M in sera of some patients with multiple sclerosis

Fraser, K.B.; Armstrong, M.; Shirodaria, P.V.; Gharpure, M.

Clinical and Experimental Immunology 36(2): 304-310

1979

ISSN/ISBN: 0009-9104
PMID: 383332
Document Number: 142841
HEp2 G specific for measles virus hemolysin could be recognized in multiple sclerosis (MS) sera and that in some sera from which rheumatoid factor was removed, a residual IgM (MS-IgM) was absorbed to measles virus-infected cells and showed the same specificity in blocking tests as measles virus anti-hemolysin. MS-IgM could be removed from sera by absorption with latex particles coated with human IgG and may be anti-globulin with preferential affinity for anti-hemolysin.

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