Retrospective analysis of anaesthetics received by patients before susceptibility to malignant hyperpyrexia was recognized
Halsall, P.J.; Cain, P.A.; Ellis, F.R.
British Journal of Anaesthesia 51(10): 949-954
1979
ISSN/ISBN: 0007-0912 PMID: 518796 Document Number: 142618
The anesthetic histories of patients susceptible to malignant hyperpyrexia (MH) were reviewed. Many patients having this condition were exposed to the known inducing agents previously [30 were studied, but most of the concentation was placed on halothane and suxamethonium], sometimes on more than 1 occasion. Insusceptibility to MH cannot be assumed from previous uneventful exposure to the known triggering agents. All patients suspected of having inherited MH must be screened by in vitro muscle biopsy studies. No common factor could be found to explain this phenomenon.