Effect of acute hypoxia on specific and nonspecific brain systems in rabbits
Akopyan, N.S.; Baklavadzhyan, O.G.
Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 13(6): 53-57
1979
ISSN/ISBN: 0321-5040 PMID: 502427 Document Number: 142388
At a simulated altitude of 8500-9000 m, an increase in the amplitude of the early positive and negative phase of the thalamic-cortical evoked potentials, and a slight prolongation of the latent period were seen. Changes in the reticulo-cortical and hypothalamo-cortical evoked potentials included a pronounced inhibition of their negative phase. In the EEG slow delat-waves increased gradually, becoming the major rhythm. The presence of EEG signs of the development of inhibitory processes in the cortex suggested that the changes in evoked potentials were also a result of inhibition of cortical neurons. Hypoxia-adapted rabbits tolerated acute hypoxia much better. They exhibited less pronounced changes in the electric manifestations of the function of specific and nonspecific projection systems of the brain.