Predictive value of cerebrospinal fluid polyamines in medulloblastoma
Marton, L.J.; Edwards, M.S.; Levin, V.A.; Lubich, W.P.; Wilson, C.B.
Cancer Research 39(3): 993-997
1979
ISSN/ISBN: 0008-5472 PMID: 427786 Document Number: 140199
Seventy-five cerebrospinal fluid polyamine determinations were evaluated in 16 patients with medulloblastoma. Parameters utilized in evaluating patient status for correlation with the polyamine concentrations were neurological examination, computerized tomography, radionuclide scan, myelography, and cerebrospinal fluid cytology. Fifteen of the 16 patients showed absolute correlation with the eventual clinical picture. One determination on one patient resulted in a false negative. No false positives have been observed to date.