A fatal enteric syndrome in Mystromys albicaudatus (white tailed rat) following topical antibiotic treatment

LaRegina, M.; Kier, A.B.; Wagner, J.E.

Laboratory Animal Science 28(5): 587-590

1978


ISSN/ISBN: 0023-6764
PMID: 214636
Document Number: 138277
Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs. Clinical signs included anorexia, depression, and rough hair coat. Predominant necropsy findings were hrmorrhagic typhlitis and colitis. Results of studies evaluating the roles of the anesthetic and the tropical antibiotic ointment suggested that the deaths were caused by ingestion of the topically applied antibiotic.

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