Immunocytological studies of C cells with anti-calcitonin or antisomatostatin immunoserums in rats treated with vitamin D, thyroxine or benzyl-thiouracil
Bugnon, C.; Fellmann, D.; Blahser, S.; Maurat, J.P.; Bloch, B.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 172(4): 691-696
1978
ISSN/ISBN: 0037-9026 PMID: 154950 Document Number: 137970
In rats treated with vitamin D3, thyroxin or BTU alone or with associations of vitamin D3 + BTU or vitamin D + thyroxin, immunocytochemical studies with an anti-human calcitonin serum show a stimulating effect of vitamin D and of thyroxin and an inhibiting effect of BTU on the C cells of the thyroïd. These results are in agreement with the existence of functional relations between follicular and C cells. A few calcitonin-containing cells are immunoreactive to an anti-somatostatin serum. All the C cells contain both calcitonin and somatostatin when they are grouped in a single big interfollicular cluster.