Effect of alloxan diabetes on the enzyme activity of the mucous membrane of the small intestine
Rakhimov, K.R.; Zaripov, B.Z.
Problemy Endokrinologii 24(6): 85-89
1978
ISSN/ISBN: 0375-9660 PMID: 724680 Document Number: 137943
Experiments on male rats showed that following subcutaneous injection of alloxan in a dose of 15 mg per 100 g of body weight amylolytic, invertase, glycyl-l-tyrosine dipeptidehydrolase activity of the mucosa of the small intestine altered differently. As a result, there occurred a deviation of the enzymatic spectrum from the normal characterized by a sharp increase (with the development of diabetes) of the activity of the carbohydrate hydrolysing enzymes (amylase and invertase) with a simultaneous reduction of the activity of the enzymes participating in protein (dipeptidase) and fat (monglyceridlipase) hydrolysis.