Effect of adsorption on the structure and properties of hemoglobin
Genkin, M.V.; Davydov, R.M.; Krylov, O.V.
Biofizika 23(5): 796-800
1978
ISSN/ISBN: 0006-3029 PMID: 29668 Document Number: 136082
Adsorption spectra of Hb+ and HbO2 adsorbed on silica and monolayers cholesterol supported on silica have been studied. It is shown that immobilization leads to new states of proteins, their properties depending on the nature of support and conditions of adsorption. Adsorption of haemoglobin leads to its inactivation. The rate of inactivation decreases with an increase of surface concentration of haemoglobin and with simultaneous adsorption of inert proteins.
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