Effect of the structure of polymeric materials on the properties of immobilized enzymes

Kil'deeva, N.R.; Krasovskaia, S.B.; Tsarevskaia, I.I.; Virnik, A.D.; Filippova, O.V.

Prikladnaia Biokhimiia i Mikrobiologiia 24(3): 375-379

1988


ISSN/ISBN: 0555-1099
PMID: 3174605
Document Number: 324546
The relationship between the structure of triacetate cellulose fibres and films and properties of enzymes entrapped in these materials was investigated. Trypsin and penicillin amidase were entrapped in triacetate cellulose films and fibres during their formation. The effect of permeability of the films on the catalytic properties of entrapped trypsin was studied. The porous structure of triacetate cellulose fibres with entrapped penicillin amidase was studied, the fibres being produced by different methods. An increase of porosity and the specific surface of the fibre-biocatalyst reduced the Km value and the energy of activation of the hydrolytic decomposing of benzyl penicillin but increased the Vmax value.

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