Efficacy of an in-feed ivermectin formulation against gastrointestinal helminths, lungworms, and sarcoptic mites in swine
Alva-Valdes, R.; Wallace, D.H.; Foster, A.G.; Ericsson, G.F.; Wooden, J.W.
American Journal of Veterinary Research 50(8): 1392-1395
1989
ISSN/ISBN: 0002-9645 PMID: 2782722 Document Number: 136
The efficacy of ivermectin as an in-feed formulation was evaluated against naturally acquired gastrointestinal helminths, lungworms, and sarcoptic mites (experiment 1; n = 24) and against induced infection with intestinal nematodes (experiment 2; n - 24) in pigs. Treatments consisted of ivermectin administered in feed at concentrations calculated to provide 100 or 200 .mu.g/kg of body weight/d for 7 days or or nonmedicated feed (controls) for 7 days. At concentrations of 100 .mu.g of ivermectin/kg/d, efficacy against naturally acquired infections were 97.7% for Ascris suum, 97.8% for Metastrongylus spp, > 99% for Oesophagostomum spp, 100% for Macracanthorhynchus hirudinaceus, and 89.7% for Ascarops strongylina. Against induced infections (fourth-stage larvae), efficacy ws 100% for A. suum and 96.9% for oesophagostomum spp. At concentration of 200 .mu.g of ivermectin/kg/d, efficacy against naturally acquired infections was 100% for A. suum, Hyostrongylus rubidus, Metastrongylus spp, and Ascarops strongylina; > 99% for Oesophagostomum spp; and 85.9% for Macracanthorhynchus hirudinaceus. Against induced infections (fourth-stage larvae), efficacy was 100% for A. suum and 95% for Oesophagostomum spp. At concentrations of 100 and 200 .mu.g of ivermectin/kg/d, efficacy against Sarcoptes scabiei var suis was evidenced by elimination of the mite by posttreatment day 14.
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