Evaluation of correlation between selected rheological parameters of ointments and their in vitro release data
Kasza, P.; Gyarmati, L.
Die Pharmazie 33(8): 526-527
1978
ISSN/ISBN: 0031-7144 PMID: 724783 Document Number: 134435
A comparative study was done by the authors between the active substance release characteristic of lipophilic and hydrophilic oitment bases and their rheological parameters. There was stated a significant difference due to the matrix concentration the last being an essential factor in determining the effective surface area. The water solubility of matrix constituents is plaxing an important role in formation of the effective surface area.
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