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Effect of space flight and of the accompanying radiation on amino acid metabolism in the skeletal muscle of rats

Ushakov, A.S.; Gaevskaya, M.S.; Vlasova, T.F.; Veresotskaya, N.A.; Miroshnikova, E.B.

Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 12(1): 27-31

1978

ISSN/ISBN: 0321-5040
PMID: 621908
Document Number: 134060
It was demonstrated that a combined effect of 20.5-day space flight and gamma-irradiation reduced the content of biologically important amino acids (methionine, phenylalanine, serine, aspartic and glutamic acids) and inhibited the activity of aspartate aminotransferase of sarcoplasmatic proteins in the quadriceps muscle of rats. Comparison of these data with the Cosmos-605 results and literature reports suggested that gamma-irradiation inhibited the synthetic processes in the skeletal muscle.

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