Prophylaxis of metastases formation by prolonged non-specific immunostimulation associated with heparin therapy
Kiricuta, I.; Todorutiu, C.; Risca, R.
Physiological Chemistry and Physics 10(3): 247-253
1978
ISSN/ISBN: 0031-9325 PMID: 733938 Document Number: 133257
In rats with Ehrlich ascites tumors, prolonged non-specific immunostimulation with a polymicrobial preparation significantly reduced metastases. Prolonged anticoagulant therapy with heparin was also shown to reduce metastases. Combined prolonged therapy with both agents reduced metastases significantly more than therapy with either agent alone.