Non-steroidal anti-inflammatory agents. V. Optically active 4-biphenylyloxybutyric and 4-biphenylylglycolic acids

Guarnieri, A.; Burnelli, S.; Andreani, A.; Busacchi, I.; Barbaro, A.M.; Gaiardi, M.

Il Farmaco; Edizione Scientifica 33(10): 761-769

1978


ISSN/ISBN: 0430-0920
PMID: 744235
Document Number: 132038
The synthesis and the resolution of the enantiomers of (+/-)2-(4-biphenylyl)-4-oxybutyric and (+/-)4-(4-biphenylyl)-2-oxybutyric acids and the resolution of the enantiomers of (+/-)2-(4-biphenylyl)-2-oxybutyric and (+/-)4-biphenylylglycolic acids are described. The potassium salts of each enantiomer were submitted to preliminary assays of antiphlogistic activity.

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