Non-steroidal anti-inflammatory agents. V. Optically active 4-biphenylyloxybutyric and 4-biphenylylglycolic acids
Guarnieri, A.; Burnelli, S.; Andreani, A.; Busacchi, I.; Barbaro, A.M.; Gaiardi, M.
Il Farmaco; Edizione Scientifica 33(10): 761-769
1978
ISSN/ISBN: 0430-0920 PMID: 744235 Document Number: 132038
The synthesis and the resolution of the enantiomers of (+/-)2-(4-biphenylyl)-4-oxybutyric and (+/-)4-(4-biphenylyl)-2-oxybutyric acids and the resolution of the enantiomers of (+/-)2-(4-biphenylyl)-2-oxybutyric and (+/-)4-biphenylylglycolic acids are described. The potassium salts of each enantiomer were submitted to preliminary assays of antiphlogistic activity.