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Effect of gentamycin, decamethoxin and prodigiozan on the course and outcome of experimental pyocyanic infection in white mice

Volianskiĭ, I.L.; Korpan, A.I.; Paliĭ, G.K.

Antibiotiki 23(3): 254-257

1978

ISSN/ISBN: 0003-5637
PMID: 345960
Document Number: 131359
The therapeutic and prophylactic effectiveness of gentamicin, decamethoxin and prodigiozan was determined on albino mice infected with 2-fold lethal doses of the antibiotic-resistant strain of Pseudomonas aeruginosa. Correlation between the effectiveness of the drug and the dose and time of its administration was found. Pronounced prophylactic and therapeutic effect of gentamicin in combination with decamethoxin was noted. Prodigiozan, a bacterial polysaccharide, had no significant effect on the experimental pyocyanic infection of albino mice.

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