Effect of thyrocalcitonin on mineral metabolism in experimental osteoporosis
Golinskaia, M.S.
Farmakologiia i Toksikologiia 41(3): 334-338
1978
ISSN/ISBN: 0014-8318 PMID: 658384 Document Number: 130769
By the method of radioactive indication of ashed specimens of the femur, tibia, jaw bones and molars on a model of experimental osteoporosis in rats it is shown that the degree of mineralization of calcified tissues increases under the effect of thyrocalcitonin (TCT). The hypermineralization of jaw bones and, especially, of molars was attended by a lower 45Ca inclusion in these tissues. The structure of the adrenal cortex, kidneys, pancreas and thyroid returned back to normal under the effect of TCT and with carbohydrate rich nutrition, this occurring against the background of a high 45Ca concentration in these organs.