General hemodynamics and kidney function in hypertension in pregnant women
Shekhtman, M.M.; Glezer, G.A.
Kardiologiia 18(11): 77-84
1978
ISSN/ISBN: 0022-9040 PMID: 31508 Document Number: 129015
The indices of general hemodynamics and renal function were studied in 362 pregnant women (healthy and those suffering from hypertensive disease, glomerulonephritis or nephropathy) and in 20 healthy but not pregnant women. It was found that the hypokinetic type of circulation developed in glomerulonephritis and nephropathy in pregnant women and that the hyperkinetic type changes to eu- and hypokinetic types in pregnant women suffering from hypertensive disease. In all variants of hypertension in pregnancy, the renal blood flow and glomerular filtration reduce, while the resistance to the blood flow in the vessels of the kidneys increases. The role of the sympathetico-adrenal and the renin-aldosterone systems in the changes in hemodynamics and renal function in healthy and sick pregnant women was studied. An opinion is voiced that increased sensitivity of the vascular receptors to vasoactive substances is very important.