Strongyloides ratti infections in rats. I. Immunopathology
Olson, C.E.; Schiller, E.L.
American Journal of Tropical Medicine and Hygiene 27(3): 521-526
1978
ISSN/ISBN: 0002-9637 PMID: 307918 Document Number: 128838
The elimination of adult parasites from the intestines of rats after a first and 2nd infection of Strongyloides ratti was studied. Expulsion after a 2nd infection was anamnestic, indicating that the response is immunological. Intestinal mast cell responses accompanied damage and expulsion of worms, the secondary mast cell response being more rapid but less intense that the first. Anti-thymocyte serum suppressed expulsion as well as both the intestinal mast cell and circulating eosinophil responses to primary infection. [AS].