Colonic protection from dimethylhydrazine by a high fiber diet
Chen, W.F.; Goldsmith, H.S.
Surgery Gynecology and Obstetrics 147(4): 503-506
1978
ISSN/ISBN: 0039-6087 PMID: 705568 Document Number: 128223
Results of this experiment showed that a high fiber bran diet had the ability to lower significantly the incidence of pathologic changes in the colon of mice receiving 1,2-dimethylhydrazine, a drug known for its specificity for causing carcinoma of the colon. This finding adds support to the hypothesis which clains that the addition of bran to the diet has the ability to lower the indicence of carcinoma of the large intestine.