Measles virus meningoencephalitis. Immunofluorescence study of brains infected with virus mutants
Woyciechowska, J.; Breschkin, A.M.; Rapp, F.
Laboratory Investigation; a Journal of Technical Methods and Pathology 36(3): 233-236
1977
ISSN/ISBN: 0023-6837 PMID: 320383 Document Number: 124038
The localization of measles virus antigens in hamster brains inoculated with a temperature-sensitive mutant of measles virus r its revertant was studied by immunofluorescence. We found significantly less virus antigen in mutant-inoculated than in revertant-inoculated brains. In mutant-inoculated brains the virus antigens were very often found in the meninges. Possible mechanisms for the development of experimental hydrocephalus and meningoencephalitis are discussed.
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