Experimental study of bioresolving preparations of immobilized fibrinolysin
Chazov, E.I.; Mazaev, A.V.; Torchilin, V.P.; Lebedev, B.S.; Il'ina, E.V.
Kardiologiia 17(11): 139-142
1977
ISSN/ISBN: 0022-9040 PMID: 146106 Document Number: 123942
The 1st part of a multistep analysis of immobilized fibrinolysin on modified Sephadex during thromboembolism of the femoral artery in dogs is presented. A definite thrombolytic effect of fibrinolysin, prolonged on modified Sephadex microspheres was observed. Intraarterial injection of Sephadex microspheres in adequate doses did not produce damaging effects. Applications for oncological and endocrinological therapy are proposed.
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