Clinico-experimental study of using plant preparations from the flowers of Filipendula ulmaria (L.) Maxim for the treatment of precancerous changes and prevention of uterine cervical cancer
Peresun'ko, A.P.; Bespalov, V.G.; Limarenko, A.I.; Aleksandrov, V.A.
Voprosy Onkologii 39(7-12): 291-295
1993
ISSN/ISBN: 0507-3758 PMID: 7825300 Document Number: 415678
The paper reports the results of the experimental and clinical evaluation of the administration of drugs prepared from flowers of Filipendula ulmaria (L.) Maxim for cervical dysplasia and cancer treatment. Local administration of decoction resulted in a 39% drop in the frequency of squamous-cell carcinoma of the cervix and vagina induced in mice by 7,12-dimethyl-benz(a)anthracene treatment. Positive response was recorded in 32 patients (67%), including 25 cases (52%) of complete regression of dysplasia, out of 48 cases of cervical dysplasia treated with courses of ointment application. No recurrence was observed in 10 completely cured patients within 12 months.