Gemcitabine and radiotherapy in the treatment of uterine cervical cancer patients at Phramongkutklao Hospital
Jarruwale, P.; Tanapat, Y.; Aimpun, P.
Journal of the Medical Association of Thailand 88(Suppl 3): S19-S24
2005
ISSN/ISBN: 0125-2208 PMID: 16858940 Document Number: 9032
To determine response, complication and survival of uterine cervical cancer patients treated with concurrent gemcitabine radiotherapy. A retrospective review of medical records of 41 patients with uterine cervical cancer patients, stage IIB and above treated with concurrent gemcitabine radiotherapy from August 2000 to August 2003. At 6 and 12 months of follow up, the complete response rate was 75.6% and 65.9%. The cumulative probability of survival at 6 and 12 months after treatment was 0.93 and 0.85. The main complications were mild hematologic and nonhematologic toxicities. Concurrent gemcitabine radiotherapy provided a satisfactory response in patients with uterine cervical cancer with mild toxicity. Long term follow up data is necessary to determine the recurrent rate of this regimen.